Efficacy of Hangekobokuto on Patients with Functional Dyspepsia, with Special Reference to its Clinical Indication and Gastrointestinal Function
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- OIKAWA Tetsuro
- Oriental Medicine Research Center, Kitasato University
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- ITO Go
- Oriental Medicine Research Center, Kitasato University
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- HOSHINO Takayuki
- Oriental Medicine Research Center, Kitasato University Doctoral Program of Medical Science, Kitasato University Graduate School
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- HAYASAKI Tomoyuki
- Oriental Medicine Research Center, Kitasato University
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- TAKAHASHI Yuko
- Oriental Medicine Research Center, Kitasato University
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- YASHIRO Shinobu
- Oriental Medicine Research Center, Kitasato University Doctoral Program of Medical Science, Kitasato University Graduate School
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- GONO Yukari
- Oriental Medicine Research Center, Kitasato University
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- ODAGUCHI Hiroshi
- Oriental Medicine Research Center, Kitasato University
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- HANAWA Toshihiko
- Oriental Medicine Research Center, Kitasato University Doctoral Program of Medical Science, Kitasato University Graduate School
Bibliographic Information
- Other Title
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- 半夏厚朴湯の使用目標とその臨床効果との関連について―機能性ディスペプシア患者における検討―
- ハンゲコウボクトウ ノ シヨウ モクヒョウ ト ソノ リンショウ コウカ トノ カンレン ニ ツイテ キノウセイ ディスペプシア カンジャ ニ オケル ケントウ
- ─機能性ディスペプシア患者における検討─
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Description
We have limited evidence as to the clinical indications for Kampo medicines, especially as they relate to gastrointestinal function. Thus, we investigated the efficacy of the Kampo medicine hangekobokuto (HKT) on patients with functional dyspepsia (FD), with special reference to its clinical indications for gastrointestinal function, including gastric emptying and bowel gas volume.<br>Gastric emptying rate (GER) in FD patients was significantly facilitated by HKT. HKT also improved the gastrointestinal symptoms of the patients. Among these, patients who had inchuusharen, or a symptom of globus sensation, and a representative indication for HKT, showed significant improvement of both their GER and gastrointestinal symptoms compared with patients who did not have inchuusharen. As for bowel gas, the bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients decreased significantly, after administration of HKT. Patients who had fukuman, or a feeling that one's stomach is full or bloated, and another representative indication for HKT, showed significant decrease of their GVS to normal levels, compared with patients who did not present with fukuman.<br>These results suggest that the presence of clinical indications, such as inchuusharen or fukuman, are strongly related to HKT efficacy in patients with FD, and that these are useful, scientifically validated markers for the efficient use of HKT.
Journal
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- Kampo Medicine
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Kampo Medicine 59 (4), 601-607, 2008
The Japan Society for Oriental Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390282679885756800
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- NII Article ID
- 110006862060
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- NII Book ID
- AN00015774
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- ISSN
- 1882756X
- 02874857
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- NDL BIB ID
- 9611896
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed