Re-evaluation of Platelet Concentrates Stored at 4.DEG.C..
-
- Saigo Katsuyasu
- Blood Transfusion Division, Kobe University Hospital
-
- Hashimoto Makoto
- Blood Transfusion Division, Kobe University Hospital
-
- Yamamoto Mitsuteru
- Blood Transfusion Division, Kobe University Hospital
-
- Matsumoto Hideaki
- Sysmex Corporation
-
- Ohara Kiyoko
- Hyogo Red Cross Blood Center
-
- Omura Takeshi
- Hyogo Red Cross Blood Center
-
- Kohsaki Masatoshi
- Hyogo Red Cross Blood Center
-
- Mito Hisashi
- Hyogo Red Cross Blood Center
-
- Ryo Ryukichi
- Faculty of Health Science, Kobe University School of Medicine
-
- Kumagai Shunichi
- Blood Transfusion Division, Kobe University Hospital
-
- Jiang Meiyi
- Sysmex Corporation
Bibliographic Information
- Other Title
-
- ４℃保存血小板製剤の再評価
Search this article
Abstract
We evaluated the feasibility of storage of platelet concentrate (PC) at 4°C. Although the number of platelets in PCs decreased during storage at both 4°C and room temperature (RT), PCs stored at 4°C had significantly fewer platelets after 5-day storage, but showed superior platelet aggregation to that of PCs stored at RT. At the same time, β-thromboglobulin (β-TG) release reaction was also detected in PCs stored at 4°C. RANTES, p-selectin and β-TG accumulation during PC storage at 4°C was less than that of PCs stored at RT. Although it is known that no in vitro test has been shown to correlate well with platelet in vivo survival and recovery, our results may indicate that it is worthwhile to re-evaluate the efficacy of PC storage at 4°C.
Journal
-
- Journal of the Japan Society of Blood Transfusion
-
Journal of the Japan Society of Blood Transfusion 46 (5), 480-486, 2000
The Japan Society of Transfusion Medicine and Cell Therapy
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679885927296
-
- NII Article ID
- 10010139614
-
- NII Book ID
- AN00198368
-
- ISSN
- 18838383
- 05461448
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed