- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- 【Updated on June 30, 2025】Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
A Case of Sleep Apnea Syndrome Improved after Administration of Hange-koboku-to.
-
- HISANAGA Akito
- Furusato Hospital
-
- ITOH Takashi
- Deparment of Kampo Diagnostics, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
-
- NIIZAWA Atsushi
- Department of Japanese Oriental (Kampo) Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
-
- YOKOYAMA Koichi
- Department of Japanese Oriental (Kampo) Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
-
- KITA Toshiaki
- Deparment of Kampo Diagnostics, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
-
- TERASAWA Katsutoshi
- Department of Japanese Oriental (Kampo) Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Bibliographic Information
- Other Title
-
- 半夏厚朴湯が有効であった睡眠時無呼吸症候群の1例
Search this article
Description
We report a case of obstructive sleep apnea syndrome effectively treated with Hange-koboku-to. A 32-year-old male suffered from globus syndrome (globus hystericus), excessive daytime sleepiness and snoring. He underwent uvulopalatopharyngoplasty at the age of 27, but the symptoms did not improve after surgery. Nocturnal polysomnography, performed before administration of Hange-koboku-to, confirmed the diagnosis of obstructive sleep apnea syndrome. After 1-month-administration of Hange-koboku-to extract (Tsumura Co. Ltd., 7.5g/day), his complaints almost disappeared. After 5-month-administration of Hange-koboku-to, nocturnal polysomnography was performed again. As a result, the apnea index fell from 19.2 events/hour to 10.3 events/hour, and the apnea-hypopnea index also fell from 19.2 events/hour to 12.8 events/hour. He was not obese (body mass index: 23.0kg/m2), and no significant body weight change was observed after administration. No adverse effect was observed. To our knowledge, there is no other report on the treatment of sleep-related breathing disorders with Hange-koboku-to. We presume that Hange-koboku-to may decrease the upper airway resistance, especially at the lower part of the upper airway.
Journal
-
- Kampo Medicine
-
Kampo Medicine 52 (4/5), 501-505, 2002
The Japan Society for Oriental Medicine
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282679886115072
-
- NII Article ID
- 110004003707
-
- NII Book ID
- AN00015774
-
- ISSN
- 1882756X
- 02874857
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed