Pharmaceutical Care to a Patient with Dysphagia Who Needs Gefitinib Chemotherapy

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  • 内服困難な患者に対するゲフィチニブ投与に薬剤師が効果的に介入できた１例
  • 症例報告 内服困難な患者に対するゲフィチニブ投与に薬剤師が効果的に介入できた1例
  • ショウレイ ホウコク ナイフク コンナンナ カンジャ ニ タイスル ゲフィチニブ トウヨ ニ ヤクザイシ ガ コウカテキ ニ カイニュウ デキタ 1レイ

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  Recently, in order to make chemotherapy, safer and more effective various forms of intervention by pharmacists are needed. In this paper, we report our experience in intervening in the administration of gefitinib to a patient with dysphagia. Chemotherapy with an intravenous drip injection to the 58 year-old woman admitted to our hospital for non-small cell lung cancer (NSCLC) was withdrawn due to severe pancytopenia after the first cycle of pharamcotherapy. Then, as an altermative, oral medication, of gefitinib was suggested by medical doctors. However, the oral administration was inappropriate to the condition of the patient. She was unable to keep taking gefitinib pills because she had been suffering from a progressive swallowing disturbance due to progressive non-small cell lung cancer. Thus, we proposed another oral administration method in which gefitinib was resuspended in thickening agents. This method made it possible for the patient to take gefitinib without any adverse events until the day before the patient died.

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