A serious intoxication case of organofluorine pesticide “NISSOL”

  • Kuroda Masahiro
    The First Department of Internal Medicine, Hirosaki University School of Medicine
  • Tonomura Kichiya
    The First Department of Internal Medicine, Hirosaki University School of Medicine
  • Kuroda Michiko
    The First Department of Internal Medicine, Hirosaki University School of Medicine
  • Terada Kiyoshi
    Department of Internal Medicine, Hirosaki City Hospital

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Other Title
  • 農薬・有機フッ素剤中毒重症型の1治験例
  • ノウヤク ユウキ フッソザイ チュウドク ジュウショウガタ ノ 1チケンレイ

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Abstract

A 51 years old farmer was in unconscious state when he was brought into our hospital. Four days before admission he handled “Nissol” and low toxic organophshor “Smithion” about 9 hours at his farm of apples.<BR>Three days before he noted nausea, vomiting, headache, dizzines, sweatiness and light fever. In the midnight convulsion of limbs occured. Two days before symptoms became progressively worse.<BR>Examinations on admission revealed depression of blood pressure (100-70), incipient rise of body temperature, low blood sugar level (45 mg/dl), concussion of eye-ball and Babinski's sign.<BR>Then as an intoxication of Nissol we treated the patient with glucose solution (5 or 50%), acetamide, antibiotics, phenobalbital, cardiac stimulants and atropin. Fourteen hours after admission he recovered consciousness.<BR>Low blood sugar level and depression of blood pressure continued while about 7 days.<BR>He was out of hospital on the 20 th day.

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