Normal Range Calculation: Selecction of the Distribution Which Conform to Mean, Standard Deviation and Skewness

  • USUI TOSHIAKI
    Department of Laboratory Medicine, Nagasaki University Hospital

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  • 正常値計算法: 平均, 標準偏差, 歪度に適合する分布の選択法

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A Statistical distribution model (dislocated lognormal distribution). which is convertible to normal distribution after transformation of the variable by log (x-a), is adopted as a model for normal range calculation. The distribution parameters are calculated from sample statistics (mean, standard deviation and skewness). The distribution conform well to non-normal and non-lognormal distributions. Calculated normal ranges are makedely affected by a few cases of abnormal data, and the method is only applicable to pure normal samples.

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