書誌事項
- タイトル別名
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- Cytogenetic Effects of 2, 4, 5-trichlorophenoxyacetic Acid
- 2 4 5 T ニヨル センショクタイ イジョウ
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説明
The pollution of our environment by a variety of mutagenic agents has been at issue in the last few years. The herbicide 2, 4, 5-trichlorophenoxyacetic acid (2, 4, 5-T) has turned out to be a potent mutagenic agent. Therefore, we evaluated the cytogenetic effect of this compound on the human leukocyte in vitro. Chromatid aberrations were observed and it was found that their incidence increases in proportion to a rise in dose.<BR>It has been claimed that the teratogenic effects of 2, 4, 5-T may be attributed to the presence of 2, 3, 7, 8-tetrachlorobenzo-p-dioxin (dioxin) as an impurity. The compound used in our study contained 0.09μg/g of dioxin. Although the level of contamination is low, the possible roleof dioxin cannot be ruled out. Nevertheless, the fact remains that the mutagenic effects of the compound now available are undeniable.
収録刊行物
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- 日本農村医学会雑誌
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日本農村医学会雑誌 24 (2), 77-79, 1975
一般社団法人 日本農村医学会
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詳細情報 詳細情報について
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- CRID
- 1390282679889022848
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- NII論文ID
- 130004383785
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- NII書誌ID
- AN00196216
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- ISSN
- 13497421
- 04682513
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- NDL書誌ID
- 1612328
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