A Case of Large Liver Cyst with Extraordinally High Level of CA19-9 in the Serum, CA19-9 and CEA in the Cystic Fluid.

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  • 血中CA19‐9および嚢胞液中のCA19‐9,CEAが異常高値を示した巨大肝嚢胞の1例

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The patient was 68-year-old woman. The abdominal echograms and CT scans revealed a large cyst in the left lobe of the liver. The CA19-9 showed a high level of 356U/ml in the serum. Three weeks later, the level increased 565U/ml. We believe that the high serum level of CA19-9 was due to the large liver cyst since we could not find any other foci such as pancreatic or gastrointentinal disease. Percutaneous cystic needle aspiration showed serous fluid with extremely high levels of CA19-9 of 2400, 000U/ml and CEA of 2, 438ng/ml. The result of cytological examination proved benign. The serum showed a normal level of 18.3U/ml two weeks after the left hepatic lobectomy. The result of histological examination of the cyst proved benign. Localization of the CA19-9 and CEA was positive in immunohistochemical staining of the epithelium of the cyst wall. We conclude that high levels of tumor markers in the serum do not necessarily indicate malignant change. This case showed quite a rare large liver cyst with abnormally high levels of CA19-9 in the serum and CEA in the fluid.

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