A Case of Progressive Respiratory Failure Resulting from Chronic Bird Fancier's Disease after Postoperative Chemotherapy

  • SHINOHARA Yoko
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • KIYOKI Yusuke
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • ANDO Keita
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • OKAWA Tyuta
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • YAMANA Takashi
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • NISHIYAMA Naoki
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • KAWAKAMI Naoki
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • WAKAI Yoko
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • YAMASHITA Takaaki
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • SAITO Kazuhito
    Depts. of Respiratory Medicine, Tsuchiura Kyodo General Hospital
  • ONUKI Takuya
    General Thoracic Surgery, Tsuchiura Kyodo General Hospital
  • INAGAKI Masaharu
    General Thoracic Surgery, Tsuchiura Kyodo General Hospital

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Other Title
  • 肺腺癌術後補助化学療法後の経過中に増悪を認めた慢性鳥飼病の1例
  • 症例報告 肺腺癌術後補助化学療法後の経過中に増悪を認めた慢性鳥飼病の1例
  • ショウレイ ホウコク ハイセンガン ジュツゴ ホジョ カガク リョウホウ ゴ ノ ケイカ チュウ ニ ゾウアク オ ミトメタ マンセイドリシビョウ ノ 1レイ

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Abstract

75-year-old man had the right lower lobe resected because of pulmonary adenocarcinoma (stage IIB) and received 4 courses of postoperative chemotherapy 4 years earlier. Thereafter, he continued to complain of cough, sputum, and progressive exertional breathlessness. The preoperative chest CT showed ground glass opacity (GGO) at the bottom of both lung fields, and over time the GGO changed to honeycombing with traction bronchiectasis. He was administered prednisolone, clarithromycin, and pirfenidone but with little improvement. He exhibited hypoxemia (PaO2 56 mmHg) and was admitted. An interview revealed that he had worked in the poultry farming business for 45 years having had contact with and breeding 3,000 game fowl at the time of hospitalization. We suspected bird-related hypersensitivity pneumonitis. Results of the reaction to pigeon dropping extracts (PDE) were high, with PDE IgG 0.697 and PDE IgA 0.445. He was diagnosed with chronic bird-related hypersensitivity pneumonitis. Although the chest CT appearance was difficult to distinguish from that of idiopathic interstitial pneumonia, the test for PDE and the interview were useful for reaching a diagnosis.

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