EFFECT OF THIAMINE TETRAHYDROFURFURYL DISULFIDE (TTFD) ON PHYSICAL FITNESS CHIEFLY ON MUSCLE STRENGTH

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  • NISHIYAMA ISSEI
    <I>Juntendo University, School of Medicine, Public Health Department</I>
  • TANAKA TSUNEO
    <I>University of Tokyo, Faculty of Medicine, Health Administration Department</I>
  • TSUMURA DAIHACHI
    <I>University of Tokyo, Faculty of Medicine, Health Administration Department</I>

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Other Title
  • Thiamine Tetrahydrofurfuryl Disulfide (TTFD) の体力特に筋力に及ぼす効果について
  • Thiamine Tetrahydrofurfuryl Disulfide(TTFD)の体力特に筋力に及ぼす効果について 二重盲検比較対照試験による検討
  • Thiamine Tetrahydrofurfuryl Disulfide TTFD ノ タイリョク トクニ キンリョク ニ オヨボス コウカ ニ ツイテ ニジュウ モウケンヒカク タイショウ シケン ニ ヨル ケントウ
  • -DOUBLE BLIND STUDIES-
  • ―二重盲検比較対照試験による検討―

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The effect of TTFD chiefly on muscle strength in athletes, mainly track and field, in training camp was examined. The double-blind method was used. The test group (T-group) was given 150mg/day of TTFD while the control group (P-group) was given 3mg/day of TTFD. The duration of administration was two weeks. The following results were obtained.<BR>1) In the following test items, T-group (150mg/day) showed higher values than P-group (3mg/day) in a significant difference:<BR>sargent test (morning) at 5% level<BR>sargent test (evening) at 2.5% level<BR>left grip strength (evening) at 5% level<BR>right grip strength (morning) at 10% level<BR>No significant differences were found in other test items.<BR>2) In the P-group, difference between 2 week stage (non-treated period) and 4 week stage (treated period) was observed to have a trend for decline in the various test items. On the contrary, in the T-group, no decline was observed and a trend for a rise was found in all test items.<BR>3) No adverse effects attributable to TTFD were noted with administration of 3mg/ day nor 150mg/day for 2 weeks.<BR>4) The influence of administration of TTFD 150mg/day was discussed on effectiveness of training as shown by the increase of motor ability.

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