Splenic Sarcoidosis without an Extrasplenic Lesion That Developed Iridocyclitis Postoperatively

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  • 術後に眼病変で再発した脾限局性サルコイドーシスの1例

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Abstract

<p>A 74-year-old woman had an intensive examination at a local hospital for lumbago. Multiple lesions were detected in the spleen on CT. Gastrointestinal endoscopy and total colonoscopy showed no abnormal findings, and PET-CT showed abnormal FDG-uptake only in the spleen. These findings were suggestive of malignant lymphoma and the patient was referred to our hospital for histological diagnosis. Laparoscopic splenectomy was performed. Histopathologically, it was characterized by a large number of noncaseating granulomas composed of epithelioid cells and multinucleated giant cells with asteroid bodies, and splenic sarcoidosis was diagnosed. The patient became disease-free but iridocyclitis occurred 3 months after surgery. We diagnosed the recurrence of the sarcoidosis. To the best of our knowledge, splenic sarcoidosis without extrasplenic lesions that recur in other organs postoperatively is rare. Therefore we report our experience with a review of the literature.</p>

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