Schwannomatosis with Intraspinal Lesion: A Report of Three Cases

DOI 1 Citations 10 References
  • Mizutamari Masaya
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Sei Akira
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Yakushiji Toshitake
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Fujimoto Toru
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Taniwaki Takuya
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Fukuda Kazuaki
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan
  • Mizuta Hiroshi
    Department of Orthopedic Surgery, Faculty of Medicine, Kumamoto University, Kumamoto, Japan

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  • 脊柱管内病変を伴うＳｃｈｗａｎｎｏｍａｔｏｓｉｓの３例

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Abstract

We report three patients diagnosed with schwannomatosis with intraspinal lesion. Case 1: A 44- year-old male presented right plexus schwannoma, and underwent operation. During observation, MRI showed an abnormal lesion at C7/ Th1. The tumor was extirpated. Pathological diagnosis was schwannoma. Case 2: A 34-year-old male complained of low back pain and right thigh numbness. Right thigh schwannoma had been resected at age 33. MRI showed an abnormal lesion at Th12/L1. The tumor was extirpated. Pathological diagnosis was schwannoma. Case 3: A 36- year-old female complained of back pain and right buttock pain. Right calf and back schwannoma had been resected between age 19 and 32. MRI showed four abnormal lesions from L1 to S1. The tumors were extirpated. One year after the operation, the remaining tumor increased and was extirpated. Pathological diagnosis was schwannoma.<BR>All three cases showed no auditory disorder, no blurred vision, no Cafe au Lait spots and no family history.<BR>Schwannomatosis is rare. If multiple lesions of neurioma are found, general investigation is needed suspecting potential schwannomatosis, NF 1 and NF 2. In case of rapidly increasing lesions, a follow-up MRI is needed. We experienced a case whose tumor had to be extirpated in the first operation.

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