^1H-MRI and in vivo ^<31>P-MRS study of diseased state of smoky-brown cockroach infected with cockroach densovirus

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  • デンソウイルスを感染させたクロゴキブリの核磁気共鳴法による体内代謝の研究
  • デンソウイルスを感染させたクロゴキブリの核磁気共鳴法による体内代謝の研究〔英文〕
  • デンソ ウイルス オ カンセンサセタ クロゴキブリ ノ カク ジキ キョウメイ

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The nuclear magnetic resonance (NMR) technology was applied to the smoky-brown cockroach, Periplaneta fuliginosa (Serville), which had been infected with cockroach densovirus of the family Parvoviridae to correlate the diseased state with metabolic changes of the cockroach. ^1H-magnetic resonance imaging (MRI) revealed that, when abnormality is not yet recognized, increased spin lattice relaxation time (T_1) was detected in and around the midgut or hindgut region of the infected insects. ^<31>P-magnetic resonance spectroscopy (MRS) demonstrated a decrease in the amount of arginine phosphate and, conversely, an increase in the amount of sugar phosphate, compared with uninfected insects.

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