Hyperreactio luteinalis with severe preeclampsia and fetal growth restriction

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  • OHTA Saori
    Department of Obstetrics and Gynecology, Osaka Medical College
  • HAYASHI Atsushi
    Department of Obstetrics and Gynecology, Osaka Medical College
  • OKAMOTO Atsuko
    Department of Obstetrics and Gynecology, Osaka Medical College
  • SANO Takumi
    Department of Obstetrics and Gynecology, Osaka Medical College
  • KANKI Kazuyoshi
    Department of Obstetrics and Gynecology, Osaka Medical College
  • SUZUKI Yusuke
    Department of Obstetrics and Gynecology, Osaka Medical College
  • FUJITA Daisuke
    Department of Obstetrics and Gynecology, Osaka Medical College
  • TERAI Yoshito
    Department of Obstetrics and Gynecology, Osaka Medical College
  • OHMICHI Masahide
    Department of Obstetrics and Gynecology, Osaka Medical College

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Other Title
  • 加重型妊娠高血圧腎症と重症胎児発育不全を合併したhyperreactio luteinalisの1例
  • 症例報告 加重型妊娠高血圧腎症と重症胎児発育不全を合併したhyperreactio luteinalisの1例
  • ショウレイ ホウコク カジュウガタ ニンシン コウケツアツジンショウ ト ジュウショウ タイジ ハツイク フゼン オ ガッペイ シタ hyperreactio luteinalis ノ 1レイ

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Abstract

Hyperreactio luteinalis (HL) is a condition associated with bilateral ovarian enlargement due to theca lutein cysts. It occurs commonly in pregnant patients with trophoblastic disease, occasionally in multiple pregnancies, and rarely in normal singleton pregnancy. We present an unusual case in which a 45-year-old nulliparous patient was found to have bilateral multicystic adnexal masses at 19 weeks of gestation. Due to severe preeclampsia and fetal growth restriction, she delivered by cesarean section. The ovaries had an anaplastic appearance, and a biopsy was taken during the cesarean section. Pathology revealed multiple benign theca lutein cysts. As a rare benign disease, HL is usually self-limited. However, some cases are diagnosed by unnecessary operation. Accordingly, it is important to exclude these from the differential diagnosis via magnetic resonance imaging and wedge biopsy in to avoid unnecessary surgical excision. [Adv Obstet Gynecol, 68 (2) : 106-111, 2016 (H28.5)]

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