African endemic-type Kaposi's sarcoma. A histopathologic study and flow cytometric DNA analysis of nine cases.

DOI IR HANDLE Web Site Web Site
  • ETO HIDEAKI
    Department of Pathology, Institute of Tropical Medicine, Nagasaki University
  • TORIYAMA KAN
    Department of Pathology, Institute of Tropical Medicine, Nagasaki University
  • ITAKURA HIDEYO
    Department of Pathology, Institute of Tropical Medicine, Nagasaki University
  • TAGAWA YUTAKA
    First Department of Surgery, Nagasaki University School of Medicine
  • KAMIDIGO NOAH O.
    Histology Department, Rift Valley Provincial Hospital

Bibliographic Information

Other Title
  • アフリカ風土病型カポシ肉腫
  • アフリカ風土病型カポシ肉腫--9例における病理組織学的検診ならびにフローサイトメトリー法による核DNA量解析〔英文〕
  • アフリカ フウド ビョウケイ カポシ ニクシュ 9レイ ニ オケル ビョウリ
  • A HISTOPATHOLOGIC STUDY AND FLOW CYTOMETRIC DNA ANALYSIS OF NINE CASES

Search this article

Description

Flow cytometric DNA analysis using formalin-fixed, paraffin-embedded tissues were performed on nine cases of African endemic-type Kaposi's sarcoma (KS). Histologically, these cases were classified into the following three types; granulation tissuelike (one case), angioma/angiosarcoma-like (four cases) and spindle cell (four cases). Although these three types showed a variety of cellularity and cellular atypism, there were no fundamental differences in the view point of proliferation of spindle cell. Mitotic figures were not prominent. All cases were exclusively diploid and lacked an aneuploid population by flow cytometric measurement of DNA content. These results suggest that African endemic-type KS is a less aggressive disease rather than a malignant neoplasm.

Journal

Details 詳細情報について

Report a problem

Back to top