Hybrid artificial organs. Liver.

  • AKAIKE T.
    Faculty of Technology, Tokyo University of Agriculture and Technology

Bibliographic Information

Other Title
  • ハイブリッド人工臓器 人工肝臓を例として
  • -LIVER-
  • ―人工肝臓を例として―

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Description

In order to replace the liver function, the development of the system where natural hepatocytes are immobilized in a matrix polymer might be considered as the best way. We designed lactose-carrying polystyrene derivatives (PVLA) as a substratum for hepatocyte from the viewpoint of modeling asialoglycoprotein. On PVLA-coated dish, the specific function as well as attachment of hepatocyte was successfully maintained. Moreover, with the addition of EGF, the aggregation of lots of hepatocytes was made, which has better functions and longevity.

Journal

  • Jinko Zoki

    Jinko Zoki 19 (3), 1042-1046, 1990

    JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

Details 詳細情報について

  • CRID
    1390282679932079872
  • NII Article ID
    130001733451
  • DOI
    10.11392/jsao1972.19.1042
  • ISSN
    18836097
    03000818
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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