Investigation of endotoxic substance associated with cardiopulmonary bypass.

DOI
  • NAGATA Y.
    Department of 2nd Surgery, Aichi Medical University
  • SHIOI K.
    Department of 2nd Surgery, Aichi Medical University
  • KATO S.
    Department of 2nd Surgery, Aichi Medical University
  • UWATOKO K.
    Department of 2nd Surgery, Aichi Medical University
  • MASE T.
    Department of 2nd Surgery, Aichi Medical University
  • TSUCHIOKA H.
    Department of 2nd Surgery, Aichi Medical University

Bibliographic Information

Other Title
  • 体外循環中のいわゆるエンドトキシン様物質の変動とその生体におよぼす影響に関する臨床的検討

Abstract

The object of this study is to determine whether cardiopulmonary bypass in open heart surgery is associated with elevation of plasma endotoxin concentrations. We determined the serum concentration of endotoxin (limulus positive substance) in 30 patients undergoing coronary bypass operations. Endotoxin concentrations were low and stable until institution of cardiopulmonary bypass (rinsed solution 1.4pg/ml, preanesthetic level 5.8pg/ml). The peak endotoxin concentration was 248.1pg/ml at the end of operation. The rise in endotoxin concentration may be one of the factors responsible for the prolonged postoperative recovery seen in some patients.

Journal

  • Jinko Zoki

    Jinko Zoki 21 (3), 1264-1266, 1992

    JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

Keywords

Details 詳細情報について

  • CRID
    1390282679932674816
  • NII Article ID
    130001732832
  • DOI
    10.11392/jsao1972.21.1264
  • ISSN
    18836097
    03000818
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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