書誌事項
- タイトル別名
-
- Development of an inflatable and drug-releasing coaxial double balloon catheter.
この論文をさがす
抄録
The development of a percutaneous procedure using a catheterized system with the function of drug delivery to diseased vessels has been increasingly demanded for minimized restenosis. A coaxial double balloon catheter, at the tip of which an inflatable and drug-releasing double balloon was installed, was developed. The outer balloon was fabricated to have micropores (diameters: 20 & 30μm) by an excimer laser ablation technique, from which a drug-containing solution was released upon inflation of the inner balloon. Scanning electron microscopic observations of the outer surface of the balloon indicated that laser-directed microporing including its size and distribution were precisely controlled using our technique. The outflow rate linearly increased with increase of infusion pressure. Outflow rate per pressure directly related to the pore size. These results indicate that the newly devised catheter may promise to realize local delivery of therapeutic agents at the diseased site shortly after mechanical balloon dilatation.
収録刊行物
-
- 人工臓器
-
人工臓器 24 (1), 229-232, 1995
一般社団法人 日本人工臓器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679933227520
-
- NII論文ID
- 10005624572
-
- NII書誌ID
- AN00120167
-
- ISSN
- 18836097
- 03000818
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可