Effects of enamel matrix derivative on periodontal tissue regeneration : focusing on radiographic observation

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To confirm the effectiveness of the use of enamel matrix derivative (EMD) on periodontal tissue regeneration, we performed flap operations applying EMD (EMD group) and without applying it (control group), radiographically observed the size of the alveolar bone defect, and clinically compared the two groups. Based on the size of bone defect and the three clinical parameters of gingival recession (GR), pocket depth (PD), and clinical attachment level (CAL), the EMD group presented a favorable clinical course for each observation criteion compared with the control groups. There were significant differences for all criteria except for the size of the bone defect and GR 3 months after surgery. In particular, the EMD and control groups both showed marked differences in CAL, which is a parameter of periodontal tissue destruction, on each observation, confirming the effectiveness of EMD for periodontal regeneration.

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