新しい人工生体材料の開発

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タイトル別名
  • Developmentof new biomedical materials

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説明

Based upon an experimental hypothesis that an ideal biomedical material should meet the following conditions: 1) proper tissue regeneration in a proper period, 2) complete replacement by reciepients tissue, 3) no cartinogenicity and 4) sufficient functions of the regenerated organs, we have performed several experimental studies before. Our standpoints are that a well controlled dissolvable synthetic or modified natural material might meet these conditions and we expect to be able to selectively tailor materials and introduce new properties by chemical or enzymatic treatments.<br>We choosed the bovine pericardium as original material and performed several kinds of chemical treatments on it.<br>Reconstractions of rabbit bladders were performed with these chemically treated bovine pericardiums after 70% resection of natural urinary bladder. Aceton pretreated 70% acetic anhydride and 30% acecti acid treated bovine pricardium showed acceptable resulst in substitution of the bladder tissue. Methylated and methyl-acetylated bovine pericardiums were also expected good biomedical materials in this study.

収録刊行物

  • 人工臓器

    人工臓器 5 (5), 271-275, 1976

    一般社団法人 日本人工臓器学会

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