One to 7 Years Follow up of the Specific and Non-Specific Treatment in Patients with Asthma

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  • 気管支喘息の長期治療成績(続)
  • キカンシ ゼンソク ノ チョウキ チリョウ セイセキ ゾク

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Abstract

One hundred and eighty five patients with asthma were treated for more than one year in the 7-year period, 1967 through 1974. The subjects were divided into two groups according to the treatment. The first group (159 patients) received systematic treatment intended to correct or block the pathophysiologic process leading to the manifestation of the disease, i.e. specific hyposensitization treatment, non-specific"Umstimmung"treatment with aurothioglucose, aurothiomalate, neurotropin, histaglobin, etc. The second group (26 patients) received symptomatic treatment only. The average follow-up time were 2 years and 5 months in the former group and 2 years and 8 months in the latter group. There were 74 patients who had asthma of moderate to severe degree originally and had no symptom or only occasional wheezing for long time, enough to compare the changes in the evaluation of individual subjects, as a result of the treatment in the first group, but only one showing such a definite improvement in the second group. Subjects showing complete remission for more than one year were 25 of 83 (25 per cent) treated with specific hyposensitization, 5 of 23 (22 per cent) treated with non-specific"Umstimmung"treatment, and 13 of 53 (25 per cent) treated with a combination of specific and non-specific treatment, reaching 43 of 159 (27 per cent) subjects as a whole treated systematically. It appeared that about a quarter of the systematically treated patients improved permanently irrespective of the treatment.

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