ALLERGENIC ACTIVITY OF NON-CALCINATED EGG SHELL CALCIUM
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- Ebisawa Motohiro
- (独)国立病院機構相模原病院小児科:(独)国立病院機構相模原病院臨床研究センターアレルギー性疾患研究部
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- Tachimoto Hiroshi
- (独)国立病院機構相模原病院小児科
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- Ikematsu Kaori
- (独)国立病院機構相模原病院小児科
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- Sugizaki Chizuko
- (独)国立病院機構相模原病院臨床研究センターアレルギー性疾患研究部
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- Masuda Yasunobu
- キューピー株式会社研究所
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- Kimura Mamoru
- キューピー株式会社研究所
Bibliographic Information
- Other Title
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- 卵殻未焼成カルシウムのアレルゲン性について
- ランカク ミショウセイ カルシウム ノ アレルゲンセイ ニ ツイテ
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Abstract
Background : There is few data to prove the safety of egg shell calcium as allergen. Especially , noncalcinated egg shell calcium is not allowed to use without the description of origin of egg on food labels in Japan. Method : We evaluated the possibly contaminated egg allergens in commercial non-calcinated egg shell calcium made from egg by in vitro methodologies (SDS-PAGE, western blotting, inhibition ELISA and sandwich ELISA) and by single-blind oral non-calcinated egg shell calcium challenge on 6 egg hypersensitivity patients. Resuts : The allergenic activity of non-calcinated egg shell calcium was almost negligible compared to egg white by all in vitro methods. Furthermore, six patients with egg hypersensitivity were unresponsive to oral non-calcinated egg shell calcium challenge test. Conclusion : These results indicate that there is little contamination of egg white in non-calcinated egg shell calcium, and that the allergenic activity of non-calcinated egg shell calcium is equivalent to that of calcinated egg shell calcium.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 54 (5), 471-477, 2005
Japanese Society of Allergology
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Keywords
Details 詳細情報について
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- CRID
- 1390282679963826048
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- NII Article ID
- 110002435812
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 7377060
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed