BIOTIN DEFICIENCY BY AMINO ACID FORMULA NUTRITION FOR AN INFANT WITH MILK PROTEIN ALLERGY
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- Mamada Yoko
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
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- Murata Takahiro
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
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- Taniguchi Ayumi
- Department of Dietary Environment Analysis, University of Hyogo
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- Hasegawa Yuki
- Department of Pediatrics, Shimane University School of Medicine
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- Suzuki Tetsuomi
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
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- Kohda Kyoko
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
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- Nasuno Kiyoto
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
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- Watanabe Toshiaki
- Department of Dietary Environment Analysis, University of Hyogo
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- Yamaguchi Seiji
- Department of Pediatrics, Shimane University School of Medicine
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- Ishiguro Akira
- Department of Pediatrics, Mizonokuchi Hospital, Teikyo University School of Medicine
Bibliographic Information
- Other Title
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- 牛乳蛋白アレルギー児に発症したアミノ酸調整粉末哺育によるビオチン欠乏症
- 症例報告 牛乳蛋白アレルギー児に発症したアミノ酸調整粉末哺育によるビオチン欠乏症
- ショウレイ ホウコク ギュウニュウ タンパク アレルギージ ニ ハッショウシタ アミノサン チョウセイ フンマツ ホイク ニ ヨル ビオチン ケツボウショウ
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Abstract
We reported a 4-month-old girl with biotin deficiency caused by amino acid formula. Two weeks after birth, she was diagnosed as having a milk protein allergy. After switching to amino acid formula from usual formula, her symptoms and laboratory findings became normal. About three weeks after the beginning of amino acid formula, she developed intractable skin erosions around the eyes, mouth, neck, and anogenital area. By measuring concentrations of some trace elements, she was diagnosed as having a biotin deficit, because of the organic aciduria and undetectable serum biotin concentration. Her serum biotinidase level was normal. Upon administration of oral biotin supplementation, all her symptoms and laboratory findings were dramatically improved. Since amino acid formula contains very few biotin, we should pay attention to biotin deficiency when infants receiving amino acid formula.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 57 (5), 552-557, 2008
Japanese Society of Allergology
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Keywords
Details 詳細情報について
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- CRID
- 1390282679967475968
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- NII Article ID
- 110006684410
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 9521158
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed
