A CASE OF FOOD PROTEIN-INDUCED ENTEROCOLITIS SYNDROME INDUCED BY SHORT-NECK CLAM INGESTION

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  • アサリによるFood protein-induced enterocolitis syndromeの1例
  • 症例報告 アサリによるFood protein-induced enterocolitis syndromeの1例
  • ショウレイ ホウコク アサリ ニ ヨル Food protein induced enterocolitis syndrome ノ 1レイ

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A 6-year-old boy was referred for evaluation because he had several vomiting episodes, from the age of 2 years, following short-neck clam ingestion. He tested negative for short-neck clam-specific IgE just before visiting our hospital, and he was not allergic to other foods or shellfish. The patient had low levels of short-neck clam-specific IgE (1.04UA/ml), and the skin prick test was positive for short-neck clam (4mm). The lymphocyte stimulation test was positive (5305 counts per min (cpm), stimulation index (SI)=1211%) and the patch test was positive for short-neck clam ingestion. An oral challenge test with boiled short-neck clam induced abdominal pain and vomiting 2h after ingestion, and the patient presented with increased peripheral leukocytes after 6h. He was therefore diagnosed with food protein-induced enterocolitis syndrome (FPIES) due to short-neck clam ingestion. To our knowledge, this is the first case report of FPIES induced by the intake of shellfish.

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