WHEAT ANAPHYLAXIS OR WHEAT-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS CAUSED BY USE OF A SOAP PRODUCT WHICH CONTAINS HYDROLYZED WHEAT PROTEINS. : A REPORT OF 12 CASES
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- Sugiyama Akiko
- Department of Dermatology, National Fukuoka Hospital
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- Kishikawa Reiko
- Department of Clinical Research Center, National Fukuoka Hospital
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- Nishie Haruko
- Department of Dermatology, National Fukuoka Hospital
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- Takeuchi Satoshi
- Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
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- Shimoda Terufumi
- Department of Clinical Research Center, National Fukuoka Hospital
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- Iwanaga Tomoaki
- Department of Clinical Research Center, National Fukuoka Hospital
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- Nishima Sankei
- Department of Clinical Research Center, National Fukuoka Hospital
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- Furue Masutaka
- Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
Bibliographic Information
- Other Title
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- お茶石鹸使用開始後に発症した小麦によるアナフィラキシーおよび小麦依存性運動誘発アナフィラキシーの12例
- オチャ セッケン シヨウ カイシ ゴ ニ ハッショウ シタ コムギ ニ ヨル アナフィラキシー オヨビ コムギ イソンセイ ウンドウ ユウハツ アナフィラキシー ノ 12レイ
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Abstract
Background: Recently, it has become a social problem that hydrolyzed wheat protein in facial soap can induce wheat allergy including wheat-dependent exercise-induced anaphylaxis (WDEIA). We described the clinical characteristics of the patients related. Methods: We collected 12 cases who had had a medical examination from January to October in 2010. Result: All the patients were female and mean age was 36.0±9.9 years. All of them had had no prior symptoms history of wheat allergy, they gradually developed wheat anaphylaxis or WDEIA in an average of 2 years after they started to use a soap product in question which contains hydrolyzed wheat proteins. Most patients suffered immediate contact allergic reactions after or at the time of washing their face with the soap product. 10 of 12 patients showed a low level of IgE to CAP-recombinant ω-5-gliadin. Episodes of anaphylaxis were prevented by avoiding both intake of wheat-containing foods and usage of the soap product. Conclusion: We concluded that their wheat anaphylaxis is likely to be caused by epicutaneous sensitization of the hydrolyzed wheat proteins in the soap product. It was important that physicians should know the possibility of sensitization from non-dietary antigen.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 60 (11), 1532-1542, 2011
Japanese Society of Allergology
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Details 詳細情報について
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- CRID
- 1390282679969249920
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- NII Article ID
- 110008798954
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 023423034
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed