REVERSIBLE ROENTGENOGRAPHIC PROGRESSION IN THE TREATMENT OF PULMONARY TUBERCULOSIS

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  • SATO Hiroshi
    From the Research Institute for Tuberculosis and Cancer, Tohoku University
  • OIZUMI Kotaro
    From the Research Institute for Tuberculosis and Cancer, Tohoku University
  • MOTOMIYA Masakichi
    From the Research Institute for Tuberculosis and Cancer, Tohoku University
  • KONNO Kiyoshi
    From the Research Institute for Tuberculosis and Cancer, Tohoku University

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  • 強力化学療法に伴う胸部レ線像の悪化例について
  • キョウリョク カガク リョウホウ ニ トモナウ キョウブ レセンゾウ ノ アッ

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Abstract

Radiographic worsening was found in 31 (3.3%) out of 935 patients with active pulmonary tuberculosis who received the initial treatment by combination of antituberculous drugs such as SM, INH, EB and RFP.<BR>There were no indications of diseases other than tuberculosis which are responsible for radio graphic progression.<BR>In the majority of cases, worsening of the findings on chest X-ray film was not accompanied with any other clinical problem. With continuation of therapy, areas of radiographic progression resolved within a few months.<BR>These results indicate that the change of antituberculous drugs is unnecessary, even if radio graphic progression, may be seen during intensive chemotherapy.

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