STUDIES ON THE LUNG DISEASE DUE TO

TSUKAMURA Michio, KITA Nobuhiko, SHIMOIDE Hisao, NAGASAWA Seiji, KAWAKAMI Keiji, ITO Tadao, MITANI Yoshio, OTSUKA Wataru, YOSHIMOTO Kazuo, WADA Tatsuzo, TAKAZAWA Naoyuki, KUZE Akihiko, HASEDA Yusaku

doi:10.11400/kekkaku1923.59.329

1) In the period of one year from the 1st January 1982 to the 31st December 1982, 3, 257 patients with mycobacterial lung disease were admitted to tuberculosis departments of participating hospitals. Of these, 111 were those with non-tuberculous lung mycobacteriosis. The kind of species which caused infection in these patients are shown in Table 1. The ratio of patients with non-tuberculous lung mycobacteriosis against the total number of patients including tuberculosis was 3.4%. From this ratio and the prevalence rate of active lung tuberculosis in 1982, 48.5 per 105 population, the prevalence rate of non-tuberculous lung mycobacteriosis was estimated as 1.65 per 10⁵ population.<BR>2) The prevalence rate of active lung tuberculosis is continuously decreasing from the year 1971 to the year 1982. In contrast, the prevalence rate of non-tuberculous lung mycobacteriosis is almost constant, 1 to 2 per 10⁵ population during the same period (Table 2 and Fig.1).<BR>3) The ratio of non-tuberculous lung mycobacteriosis in the total numberof hospitalized patients with lung disease is contiuously increasing (Table4).<BR>4) The kind of causative organisms and the epidemiology of non-tuberculous lung mycobacteriosis have changed in this recent decade. In the period of 1971 to 1977, the kind of species that caused lung disease were almost the same and ca. 6% belonged to M. kansasii and 90% belonged to M. avium-M. intracellulare complex. From the year 1978, the disease due to M. kansasii has increased, and the area where the disease occurs has spread from the Tokyo-Kanagawa area to all West Japan. From the year 1981, various species have appeared to cause the lung disease. In the year 1982, too, seven species have appeared as causative organisms (Table2). Now, we are probably in the days of mycobacteriosis caused by various species of organisms.

STUDIES ON THE LUNG DISEASE DUE TO

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