THE EFFECTS OF ANTITUBERCULOSIS CHEMOTHERAPY <I>IN VITRO</I> UNDER VARIOUS CONDITIONS INADEQUATE FOR THE GROWTH OF TUBERCLE BACILLI

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  • MAEKAWA Nobuo
    First Department of Medicine, Chest Disease Research Institute, Kyoto University
  • NAKANISHI Michiyasu
    First Department of Medicine, Chest Disease Research Institute, Kyoto University
  • KAWAI Mitsuru
    First Department of Medicine, Chest Disease Research Institute, Kyoto University
  • NAKAI Hitoshi
    First Department of Medicine, Chest Disease Research Institute, Kyoto University
  • IKEDA Nobuaki
    First Department of Medicine, Chest Disease Research Institute, Kyoto University

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Other Title
  • 結核菌の発育に不適当な条件と化学療法
  • ケッカクキン ノ ハツイク ニ フテキトウ ナ ジョウケン ト カガク リョウホウ 3 PAS マエ ショリ ト INH-PAS ヘイヨウ コウカ
  • III. Antituberculosis Activity of INH in Combination with PAS <I>in vitro</I> after Exposure to PAS
  • III. PAS前処理とINH・PAS併用効果

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For the purpose of evaluating the bactericidal activity of INH in combination with PAS against tubercle bacilli (H37Rv) ntituberculosis Activity of INH in Combination with PAS under the inadequate condition for the growth of tubercle bacilli, the experiment was made by exposing tubercle bacilli to PAS under the concentration of 1 mcg/ml and 10 mcg/ml before testing the bactericidal activity of INH and PAS.<BR>According to the results obtained, the bactericidal activity of INH and PAS is remarkably lowered after exposure to PAS.

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