書誌事項
- タイトル別名
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- Effects of Chlorhexidine and Monofluorophosphate Combinations on the Reduction of Dental Caries and Plaque Accumulation in Rats
- CHLORHEXIDINE オヨビ MONOFLUOROPHOSPHATE ノ
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The effects of chlorhexidine-digluconate (CHX), sodium-monofluorophosphate (MFP) and their combinations on the reduction of dental caries and plaque accumulation in rats were determined to examine the additive cariostatic property of each reagent.<BR>One tenth ml of MFP was daily dropped using a syringe on the molar teeth of Wister ratsfed the high-sucrose “diet 2000” during a 35-day experimental period. CHX was added to the drinking water.<BR>In the combination group (MFP, 0.02% F and CHX 0.001%) dental caries was reduced by 50% and the cariostatic level was higher than in the MFP group (0.02% F; 27.2 reduction%) or the CHX group (0.001%; 39.2 reduction%). The cariostatic level, however, was the same as in the MFP group (0.1 % F; 46.7 reduction%) and the CHX group (0.005%; 49.8 reduction%). In other combination groups such as MFP (0.1% F) plus CHX (0.005 %), MFP (0.1% F) plus CHX (0.001%) and MFP (0.02% F) plus CHX (0.05%) the cariostatic levels were also enhanced and dental caries reduction was 60.7, 51.6 and 56.3%, respectively. The reduction of dental plaque was not affected by a combination of MFP and CHX, but was the same as the level achieved using CHX only.<BR>These results suggest that the cariostatic properties of MFP and CHX were partially additive and a combination of them seems more effective in reducing dental caries than the single administration of either reagent.
収録刊行物
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- 口腔衛生学会雑誌
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口腔衛生学会雑誌 27 (3), 100-105, 1977
一般社団法人 口腔衛生学会
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詳細情報 詳細情報について
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- CRID
- 1390282679980835072
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- NII論文ID
- 130001313308
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- NII書誌ID
- AN00081407
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- ISSN
- 21897379
- 00232831
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- NDL書誌ID
- 1914001
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- PubMed
- 275324
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可