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- 島野 僚祐
- 愛知学院大学教養部化学教室
書誌事項
- タイトル別名
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- A Fundamental Study on Lanthanum as a Preventive of Dental Caries
- ウショク ヨボウザイ トシテノ ランタン ニ カンスル キソテキ ケンキュウ
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抄録
Lanthanum inhibits dental caries in experimental animals. The question of how lanthanum is absorbed by the enamel surface still leaves much to be studied.<BR>The items of this study were as follows:<BR>1) the relation between the concentration and the time of action of lanthanum when it is absorbed by the enamel surface;<BR>2) the concentration of lanthanum in experimental caries control and its distribution in internal organs when it is prescribed;<BR>3) quantitative analysis of the three elements La, Ca, and P by electron probe X-ray microanalyser and X-ray fluoressent spectrometer;<BR>4) various lanthanum phosphates in enamel surface seen by X-ray diffractometory.<BR>An exchange reaction of Ca and La in enamel surface occurred when an extracted human tooth was dipped in lanthanum solution and the surface become coated with lanthanum phosphate (LaPO4).<BR>After 3 days of immersion of a tooth in 2-8% of lanthanum solution, about 65% of the Ca was replaced and an equilibrium was reached. But in lanthanum solution of less than 1% replacement was slow, and in solution of 0.001% no reaction was detected.<BR>The lanthanum compounds in the enamel surface were aciduric.<BR>When lanthanum solution was given to a hamster, caries decreased clearly and 0.1%-0.01% of lanthanum solution (La: 312-31.2μg/ml) was most effective in preventing dental caries.<BR>In an acute toxicity test, La was accumulated in all the internal organs when solution of more than 1.5% were used.<BR>From this study I conclude that lanthanum fortifies the acid resistance of the teeth, that it is only slightly toxic, and that it is only slightly accumlated in internal organs.
収録刊行物
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- 口腔衛生学会雑誌
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口腔衛生学会雑誌 29 (4), 361-377, 1980
一般社団法人 口腔衛生学会
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詳細情報 詳細情報について
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- CRID
- 1390282679980952192
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- NII論文ID
- 130001313835
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- NII書誌ID
- AN00081407
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- ISSN
- 21897379
- 00232831
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- NDL書誌ID
- 2207369
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- PubMed
- 6936438
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可