Influence of Confectioners' Sugar and White Sugar on Experimental Dental Caries in the Rat and Hamster.

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  • HANDA Kihoko
    Department of Preventive Dentistry and Public Health, Faculty of Dentistry, Tokyo Medical and Dental University

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Other Title
  • ラットおよびハムスターの実験う餌における飼料中の粉糖と上白糖の影響について

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The purpose of this study was to examine plaque formation and dental caries occurrence in hamsters and rats fed a cariogenic diet containing confectioners' sugar and white sugar.<BR>Eighty-one golden hamsters were divided into two groups: Group I fed on Diet-2000 containing confectioners' sugar and Group II fed on Diet-2000 containing white sugar. In hamsters of Group I there was more plaque accumulation and more destruction of molars by caries than in Group II.<BR>One hundred sixty-five rats were divided into four groups: Group I fed on Diet-2000 containing confectioners' sugar; Group II fed on Diet-2000 containing white sugar; Group III fed on 6PMV containing confectioners' sugar; and Group IV fed on 6PMV containing white sugar. In Groups I and III there was more plaque accumulation than in Groups II and IV.<BR>For dental caries in rats the outer third fissure and the inner third fissure were assessed. Rats of Groups I and II showed higher caries scores than those of Groups III and IV in both fissures. Rats of Group I had higher caries scores than those of Group II in the outer third fissure but the differences were not significant. There was no difference in the caries scores in the inner third fissure between Groups I and II.<BR>In rats of Group III the caries scores were higher than in rats of Group IV in both fissures.

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