Salvage Surgery for Radiation Failure in Oral, Oropharyngeal, and Hypopharyngeal Squamous Cell Carcinoma

Bibliographic Information

Other Title
  • 口腔・中下咽頭癌の照射後再発例に対する救済手術の検討
  • コウクウ チュウカイントウ ガン ノ ショウシャゴ サイハツレイ ニ タイスル キュウサイ シュジュツ ノ ケントウ

Search this article

Abstract

Few reports have covered salvage surgery after radiotherapy, especially with chemotherapy for oral, oropharyngeal, and hypopharyngeal squamous cell carcinoma. The feasibility of salvage surgery is unclear. We analyzed postoperative complications and prognosis after salvage surgery for local recurrence after definitive radiotherapy. Subjects were 37 patients with oral, oropharyngeal, and hypopharyngeal squamous cell carcinoma treated from 1994 to 2003. Of these, 14 (37.8%) had postoperative complications. The complication rate was significantly high in the reconstructive operation group (p=0.031) and the chemotherapy group (p=0.049).<br>The 5-year overall survival rate after salvage surgery was 70.7%. Although there was no significant improvement, the prognosis was good in early-stage groups with primary tumors.<br>We found that salvage surgery after definitive radiotherapy was effective for recurrent oral, oropharyngeal, and hypopharyngeal squamous cell carcinoma. We stress the need to pay attention to postoperative complications in reconstructive operation and chemotherapy groups.

Journal

Citations (9)*help

See more

References(16)*help

See more

Details 詳細情報について

Report a problem

Back to top