迷路刺激の抗利尿作用に関する実験的並びに臨床的研究

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  • CLINICAL AND EXPERIMENTAL STUDIES ON THE ANTIDIURETIC EFFECT OF THE LABYRINTHINE STIMULI
  • メイロ シゲキ ノ コウリニョウ サヨウ ニ カンスル ジッケンテキ ナラビニ リンショウテキ ケンキュウ

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The author studied the influence of the labyrinthine stimuli upon waterdiuresis of the normal water-loaded man. Oliguria was seen in seven subjects out of seventeen when the-ordinary clinical stimuli (rotation or calorisation) were giver. But when the subjects shaked the head periodically (T=4 Sec.) for about five minutes during the rotation, urinary flow was. always reduced remarkably.<br> On the other hand, waterdiuresis in twenty patients of Meniere's disease was examined by-waterloading, and antidiuresis was found in four patients. This antidiuresis seemed to be-caused by the dizziness attack produced by waterload, or by the labyrinthine stimuli to which they were always exposed.<br> Mechanism of antidiuretic effect of the labyrinthine stimuli was discussed, and the author suspected that it would be due to the incresse of the serum antidiuretic substances, and in Meniere's disease, so-called "circulus vitiosus" was formed by the antidiuresis and the labyrinthine stimuli (dizziness attack).

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