口蓋扁桃のアルカリ性フオスフアターゼに関する実験的研究

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タイトル別名
  • EXPERIMENTAL STUDY ON ALKALINE PHOSPHATASE IN PALATINE TONSIL
  • 口蓋扁桃のアルカリ性フォスファターゼに関する実験的研究
  • コウガイ ヘントウ ノ アルカリセイ フォスファターゼ ニ カンスル ジッケンテキ ケンキュウ

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The alkaline phosphatase in the palatine tonsil were examined and following results obtained.<br>1) The alkaline phosphatase in the tonsil tissue was studied histochemically and biochmically, and its activity was found.<br>2) As the distributional comparison of alkaline phosphatase in the tonsil tissue of man, dog and rabbit are similar to each other, they have no differences to kind of animals.<br>3) The typical phosphatase reaction in the tonsil tissue was actively indicated to the circular dark layer and semi-circular dark zone surrounding the lymph folicles, being separated the stroma from the folicles by staining. On the other hand, the germinal center of the folicle was generally negativ to the same reaction.<br>4) The reaction changes in positivity were recognized in the circular dark layer and semi-circular dark zone. The semi-circular dark zone of the folicles attached to the criptical epithelium and lymphatic masses which are infiltrated in the stroma under epithelium, was often decreased or negative.<br>5) From the biochemical observation, the tonsils in the period of physiologic tonsilar hypertrophy were higher in the activity of alkaline phosphatase. It was higher in the school ages than adolescent and adult ages. These phenomenon were significant difference, and have been estimated that the acceleration of the tonsil function was higher than other periods.<br>6) In the expermental tonsilitis of the rabbit, the alkaline phosphatase the activity decreased slightly at early period of the inflammation, and at the peaks of inflammation and also at the period of formation of necrosis, its activity was almost negative or obviously decreased. Thereafter, in the period of three or four weeks, the activity became normal, while during this period the infiltrating leucocytes in the inflammed tissue was shown distinct reaction.<br>7) From these above mentioned results, the author discussed the relation of the theories of morphological changes of the folicles (Neo, Ueda, Nakagawa) and a hypothesis of tonsil structure and its function (Schwarz).

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