Nonspecific IgE Potential in Nasal Discharge for Diagnosing Allergic Rhinitis

DOI Web Site PubMed 2 Citations 17 References Open Access
  • Fukushima Kei
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University
  • Takeuchi Hiromi
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University
  • Morizane Rie
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University
  • Kitano Hiroya
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University NPO Japan Health Promotion Support Network
  • Sakoda Takema
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University Department of Otorhinolaryngology, Rinku General Medical Center, Izumisano Municipal Hospital
  • Enomoto Tadao
    Department of Otolaryngology, Head and Neck Surgery Faculty, Medicine Tottori University Department of Otorhinolaryngology, Rinku General Medical Center, Izumisano Municipal Hospital NPO Japan Health Promotion Support Network

Bibliographic Information

Other Title
  • アレルギー性鼻炎における鼻汁中非特異的ＩｇＥ検査の診断学的有用性の検討
  • 手技・工夫 アレルギー性鼻炎における鼻汁中非特異的IgE検査の診断学的有用性の検討
  • シュギ クフウ アレルギーセイ ビエン ニ オケル ビジュウ チュウ ヒトクイテキ IgE ケンサ ノ シンダンガクテキ ユウヨウセイ ノ ケントウ

Search this article

Description

Given that the nasal discharge of subjects with allergic rhinitis contains IgE, we studied nonspecific IgE potential in nasal discharge as a diagnostic marker for allergic rhinitis. We divided 38 adults into 2 groups, one with 22 with Japanese cedar pollinosis and one with 16 with watery rhinorrhea negative to MAST33. The pollinosis group was exposed to Japanese cedar pollen in an environmental exposure unit, and eosinophils in nasal discharge, serum total IgE, pollen-specific IgE, and local IgE in nasal discharge were examined for the 2 groups to determine IgE levels in nasal discharge using the Allerwatch® rapid test. In the pollinosis group, nasal discharge IgE correlated significantly with the number of eosinophils. The nasal discharge IgE had higher specificity than the eosinophil examination, whereas nasal discharge eosinophils had higher sensitivity than the IgE examination. We thus found that measuring IgE and eosinophils in nasal discharge is useful for clinically diagnosing allergic rhinitis.

Journal

Citations (2)*help

See more

References(17)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top