A Rare Case of Pharyngeal Mesenchymoma Demonstrating a Variety of Histopathological Findings

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  • Goto Kazutaka
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Kanaya Hiroaki
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Konno Wataru
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Nakajima Itsuo
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Fukami Satoru
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Hirabayashi Hideki
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University
  • Haruna Shin-ichi
    Department of Otorhinolaryngology, Head and Neck Surgery, Dokkyo Medical University

Bibliographic Information

Other Title
  • さまざまな組織像を呈し再発を繰り返した中咽頭原発間葉腫の1例
  • 症例報告 さまざまな組織像を呈し再発を繰り返した中咽頭原発問葉腫の1例
  • ショウレイ ホウコク サマザマ ナ ソシキゾウ オ テイシ サイハツ オ クリカエシタ チュウ イントウ ゲン ハツモン ヨウ シュ ノ 1レイ

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Abstract

We encountered a 38-years-old female patient who was complaining of an unpleasant sensation of the left cervical area due to a recurrent tumor originating from the middle pharynx. She had a history of surgically resected neurofibroma and lipoma from the anterior oropharyngeal wall respectively 5 years and 11 years previously. The preoperative diagnosis of a benign, non-epithelial neoplasm was made based on the imaging studies and surgical treatment was scheduled. An extended surgical resection of the middle pharynx including normal mucosa and a part of the tongue base was successfully accomplished. To cover the pharyngeal defect, a right antero-lateral thigh musculo-cutaneous flap was used for reconstruction. Microscopically, the surgically resected tissue showed a mixed condition of mature cartilaginous, bony and fibroadipose tissue without atypia. The final diagnosis was a benign mesenchymoma which was thought to have developed from pluripotential mesenchymal cells. We considered that the past tumorous lesions had possibly originated in those cells. Because pluripotential mesenchymal cells cannot easily be identified with ordinary histopathological examination, the determination of optimal surgical margins is difficult. In the case of mesenchymoma, substantial marginal tissue should be resected in order to prevent recurrence even in the case of a pathologically-proven benign tumor.

Journal

  • Nippon Jibiinkoka Gakkai Kaiho

    Nippon Jibiinkoka Gakkai Kaiho 117 (8), 1102-1107, 2014

    Japanese Society of Otorhinolaryngology-Head and neck surgery

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