A Retrospective Study on Parotid Carcinoma

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  • Kaminota Teppei
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine
  • Ugumori Toru
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine
  • Tomidokoro Yuichi
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine
  • Yamada Hiroyuki
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine
  • Wakisaka Hiroyuki
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine Ehime Prefectural University of Health Sciences
  • Gyo Kiyofumi
    Department of Otolaryngology-Head and Neck Surgery, Ehime University School of Medicine

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Other Title
  • 耳下腺癌50例の臨床的検討
  • ジカセンガン 50レイ ノ リンショウテキ ケントウ

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Abstract

We retrospectively analyzed the clinicopathological factors affecting survival in patients with previously untreated parotid carcinoma. The subjects were 50 patients treated in our department from 1987 through 2011. The T stage was T1, T2, T3, and T4 in 4 patients, 11 patients, 9 patients, and 26 patients, respectively. The N stage was N0, N1, and N2 in 36 patients, 3 patients, and 11 patients, respectively. The clinical stage was I, II, III, and IV in 4 patients, 10 patients, 7 patients, and 29 patients, respectively. Histopathologically, eleven tumor types were observed; mucoepidermoid carcinoma was the most common. The overall 5-year survival rate was 72.1%, and the disease-specific 5-year survival rate was 74.0% in 42 patients who received radical surgery. Twelve patients relapsed; the site of relapse was the primary site alone in 2, in the neck alone in 3 patients, in the neck with distant metastases in 2 patients, and in distant metastatic site(s) alone in 5 patients. Univariate analysis showed that significant prognostic factors for overall survival rates were the T stage, cervical lymph node metastasis, clinical stage, grade, facial nerve palsy, and tumor size. We concluded that patients at high risk of recurrence should receive adjuvant therapy to improve the therapeutic outcomes.

Journal

  • Nippon Jibiinkoka Gakkai Kaiho

    Nippon Jibiinkoka Gakkai Kaiho 117 (9), 1188-1193, 2014

    Japanese Society of Otorhinolaryngology-Head and neck surgery

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