IgG4-related Mikulicz's Disease: A Report of 3 Cases
-
- Nakada Hiroto
- Department of Otolaryngology, Saitama Medical University
-
- Shibasaki Osamu
- Department of Otolaryngology, Saitama Medical University
-
- Nakashima Masato
- Department of Otolaryngology, Saitama Medical University
-
- Yoshinami Hiroyoshi
- Department of Otolaryngology, Saitama Medical University
-
- Kase Yasuhiro
- Department of Otolaryngology, Saitama Medical University
Bibliographic Information
- Other Title
-
- IgG4関連Mikulicz病の3症例
- IgG4 カンレン Mikuliczビョウ ノ 3 ショウレイ
Search this article
Description
Introduction: We report three cases of hyper-IgG4 disease with synchronous or asynchronous lymphocytic infiltration onset, IgG4 positive plasma cell infiltration, and fibril formation in multiple exocrine glands and extranodal organs. IgG4-related sialadenitis attracting recent attention has yet to be clarified as a clinical entity.<br>Case report: Case 1, a 61-year-old man, had a submandibular gland sample showing IgG4-positive plasma cell infiltration. Case 2, a 61-year-old man, was diagnosed with IgG4-related Mikulicz's disease confirmed by a sublingual gland sample. Case 3, a 57-year-old woman, had a diagnosis of IgG4-related Mikulicz's disease confirmed based on labial and sublingual gland samples. All reported oral dryness and bilateral submandibular swelling. Cases 1 and 2 recovered following Predonine administration tapered from 30 or 20 mg.<br>Discussion: IgG4-related Mikulicz's disease must be recognized as a clinical entity, together with its diagnostic criteria and treatment. Sublingual gland biopsy should be done to confirm its diagnosis following sublingual gland swelling.
Journal
-
- Nippon Jibiinkoka Gakkai Kaiho
-
Nippon Jibiinkoka Gakkai Kaiho 113 (10), 798-804, 2010
The Oto-Rhino-Laryngological Society of Japan, Inc.
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282679988161664
-
- NII Article ID
- 10028256544
-
- NII Book ID
- AN00191551
-
- COI
- 1:STN:280:DC%2BC3cbmtVSltQ%3D%3D
-
- ISSN
- 18830854
- 00306622
-
- NDL BIB ID
- 10880748
-
- PubMed
- 21061567
-
- Data Source
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed