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- Yamamoto Masahiro
- Department of Pathology, Kyorin University School of Medicine
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- Nagahara Sadao
- Department of Pathology, Kyorin University School of Medicine
Bibliographic Information
- Other Title
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- 外傷後の肺微小塞栓症
- Report on sixteen autopsy cases of pulmonary bone marrow embolism from a viewpoint of shock lung or microembolic lung
- 肺の骨髄塞栓症16剖検例の報告 特にショック肺ないし微小塞栓肺としての考察
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Description
Morphological changes of pulmonary bone marrow embolism were examined in 16 out of 550 autopsy cases in the department in the past 7 years (1971-1978).<br>1. Pulmonary bone marrow embolism was complicated not only by fracture but also by therapy such as bone surgery and closed heart massage.<br>2. Bone marrow embolism was seen as microembolisms in the pulmonary small arteries and arterioles measuring mainly 100-500μ in diameter. Pulmonary changes were compatible with those seen in shock lung; vacuole formation in the endothelial cells, microthrombi, perivascular edema in the interstitium, hyaline membrane and hemorrhage in the alveolar space due to disturbance of microcirculation.<br>3. Post-traumatic bone marrow embolism was frequently accompanied by fat emboli and microthrombi. Therefore, the authors interpreted these findings to mean that bone marrow embolism is important as a cause of death and proposed considering the disease in terms of post-traumatic pulmonary microembolism rather than respiratory distress syndrome of shock and trauma.
Journal
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- The Japanese journal of thoracic diseases
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The Japanese journal of thoracic diseases 18 (4), 231-239, 1980
The Japanese Respiratory Society