Post-Traumatic Pulmonary Microembolism

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  • 外傷後の肺微小塞栓症
  • Report on sixteen autopsy cases of pulmonary bone marrow embolism from a viewpoint of shock lung or microembolic lung
  • 肺の骨髄塞栓症16剖検例の報告 特にショック肺ないし微小塞栓肺としての考察

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Morphological changes of pulmonary bone marrow embolism were examined in 16 out of 550 autopsy cases in the department in the past 7 years (1971-1978).<br>1. Pulmonary bone marrow embolism was complicated not only by fracture but also by therapy such as bone surgery and closed heart massage.<br>2. Bone marrow embolism was seen as microembolisms in the pulmonary small arteries and arterioles measuring mainly 100-500μ in diameter. Pulmonary changes were compatible with those seen in shock lung; vacuole formation in the endothelial cells, microthrombi, perivascular edema in the interstitium, hyaline membrane and hemorrhage in the alveolar space due to disturbance of microcirculation.<br>3. Post-traumatic bone marrow embolism was frequently accompanied by fat emboli and microthrombi. Therefore, the authors interpreted these findings to mean that bone marrow embolism is important as a cause of death and proposed considering the disease in terms of post-traumatic pulmonary microembolism rather than respiratory distress syndrome of shock and trauma.

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