The Significance of CA-50, SLX and ST-439 in Lung Cancer.

  • Hayasaka Shinichi
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Takada Minoru
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Shinohara Tsutomu
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Imamura Sumitaka
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Takifuji Nobuhide
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Kudoh Shinzou
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Matsui Kaoru
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Kusunoki Yoko
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Masuda Noriyuki
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Negoro Shunichi
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital
  • Fukuoka Masahiro
    2nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital

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Other Title
  • 肺癌におけるCA‐50,SLX, ST‐439の検討

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Description

Serum levels of CA-50, SLX and ST-439 were measured in 213 patients with lung cancer (92 adenocarcinomas, 63 squamous cell carcinomas, 37 small cell carcinomas and 21 large cell carcinomas) and 87 patients with benign lung disease.<br>The overall positive rates in patients with lung cancer were 12.8% for CA-50, 29.7% for SLX and 25.3% for ST-439. The positive rates for CA-50, SLX and ST-439 in adenocarcinoma patients were 22.8%, 42.4% and 38.0%, respectively.<br>Of the patients with benign lung disease, 4.8% were false positive for CA-50, 15.3% for SLX and 3.6% for ST-439.<br>In the patients with adenocarcinoma of the lung, the combination assay of CEA and ST-439 had a highly accurate rate (61.9%).

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