Ｄｉａｇｏｎａｌ　ｅａｒ　ｌｏｂｅ　ｃｒｅａｓｅの動脈硬化判定の有用性についての考察　　集団検診受診者における検討より

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タイトル別名
  • The evalution of the diagonal ear lobe crease(ELC) as a atherosclerotic sign.
  • Diagonal Ear Lobe Crease ノ ドウミャク コウカ ハン
  • 集団検診受診者における検討より

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It has been known that diagonal ear lobe crease (ELC) is a typical sign which appeared in a state of coronaly heart disease and vascular disease. Many studies of the diagonal ear lobe crease have been carried out in the patients with coronary heart disease, AMI and cerebral vascular disease. But as regards healthy subjects, there were few except the report which published by Moncoda et al, 1979. In this time we have investigated whether this ELC would be evaluated as one of the usefull signs of atherosclerosis in 768 subjects (30-87 years, male: 228, female: 539) on Hachijo Island. The relationship between the risk factors of atherosclerosis; obesty, hypertension, ECG abnormalities and abnormal lipid metabolism also apolipoproteins, were studied respectively. The results obtained were as follows: 1) The frequencies of ELC were significantly higher in male than in female (p<0.01). 2) The frequencies of ELC increased accordingly with aging on both sex. 3) As regards the frequencies of obesity and normal weight subjects in ELC presence group, there were no significant. 4) The frequencies of hypertension involved in ELC presence group were significantly higher than in ELC absence group (p<0.01). 5) The frequencies of abnormal ECG involved in ELC presence group were significantly higher than in ELC absence group (p<0.01). 6) The levels of TC and β-Lp were significantly higher in ELC presence group than in ELC absence group, however, TRG and HDLC had no significance (p<0.05). 7) Atherogenic Index (TC-HDLC/HDLC) in ELC presence group were significantly higher than ELC absence group (p<0.02). 8) The levels of Apo AI, AII and Apo AI/B ratio in ELC presence group were significantly lower than in ELC absence group, however, the levels of Apo B, CII, CIII and E and had no significant (p<0.1, p<0.05, p<0.1). The freruencies of abnormal lipids metabolism and hypertension in ELC presence group were significantly higher than in ELC absence group, age and sex matched, however obesity and ECG abnormalities were no significant (p<0.01). 10) The frequencies of the combination risk factors for atherosclerosis (abnomal lipids metabolism, ECG abnormalities and hypertension) in ELC presence group were significantly higher than in ELC absence group p<0.01). 11) The frequencies of the combination risk factors for atherosclerosis (abnomal lipids metabolism and hypertension) in ELC presence group were significantly higher than in ELC absence group (p<0.05). These observations suggested that there is a positive association between the diagnonal ear lobe crease and atherosclerosis, furthermore the inspection of ELC would be one of the useful clinical procedure for diagnosis of atherosclerosis.

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