Smoldering ATL Appeared in the Course of Collagen Disease-Like Symptoms. Followed by the Crisis and the Death

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  • 膠原病様症状で経過観察中にくすぶり型ATL（後に急性転化で死亡）と診断されるに至った1例

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We reported a case of smoldering adult T-cell leukemia. The patient had been suffered from Raynaud phenomenon, cutaneous sclerosis, lymphadenopathy and abdominal fullness in March 1983, and was thought as a kind of collagen diseases, for example, PSS. Eight months later, about 10% atypical cells (so called flower cells) appeared in her peripheral blood. Antibody to ATLA and proviral DNA of HTLV-I were positive at that time. From these data, she was diagnosed as ATL. In September 1984, a crisis occurred, and she died of pneumonia in January 1985, in spite of 4-course VEPA therapy. The autopsy was not done. And herpes zoster and controllable diabetes inspidus occurred in the course.

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  • Rinsho Ketsueki

    Rinsho Ketsueki 27 (10), 1928-1933, 1986

    The Japanese Society of Hematology

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