多発性骨髄腫を合併したPRCAの発生機序に関する検討

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書誌事項

タイトル別名
  • Studies of the Pathogenesis of Pure Red Cell Aplasia Associated with Multiple Myeloma
  • タハツセイ コツズイシュ オ ガッペイシタ PRCA ノ ハッセイ キジョ ニ

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抄録

Described herein is a 57 year-old woman who had pure red cell aplasia (PRCA) associated with a multitude of disorders including thymoma, multiple myeloma, splenomegaly and presence of antinuclear antibodies. In vitro colony assay were carried out to clarify whether the patient's IgG or peripheral mononuclear cells suppressed erythropoiesis. Both the IgG (M protein) and peripheral mononuclear cells suppressed CFU-E colony formation in cultures of normal bone marrow cells. It is suggested that in this case PRCA and multiple myeloma have a close relationship.

収録刊行物

  • 臨床血液

    臨床血液 27 (12), 2221-2227, 1986

    一般社団法人 日本血液学会

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