Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm

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  • Camostat mesilateが奏効した胸腹部大動脈瘤に合併した慢性DIC
  • 症例 Camostat mesilateが奏効した胸腹部大動脈瘤に合併した慢性DIC
  • ショウレイ Camostat mesilate ガ ソウコウ シタ キョウ フクブ ダイ ドウミャクリュウ ニ ガッペイ シタ マンセイ DIC

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Abstract

A 73-year-old man who had been receiving treatment for hypertension and angina pectoris was admitted to hospital following a transient ischemic attack. He was diagnosed as having chronic disseminated intravascular coagulation (DIC) complicated by a thoracoabdominal aortic aneurysm, and was treated with heparin sodium and a protease inhibitor. Although the DIC was controlled, the patient had to remain hospitalized in order to receive the medication by continuous infusion. Therefore, the heparin sodium and protease inhibitor were replaced by camostat mesilate, a drug suitable for oral administration and widely used for treatment of chronic pancreatitis. The drug proved effective for the chronic DIC, thus allowing the patient to receive regular treatment on an outpatient basis, and improving his quality of life.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 42 (1), 30-34, 2001

    The Japanese Society of Hematology

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