Successful Emergency Operation for Subdural Hematoma and Acute Epidural Hematoma in a Patient with Acute Promyelocytic Leukemia.

DOI PubMed 1 Citations 4 References
  • YAMAJI Satoshi
    First Department of Internal Medicine, Yokohama City University of Medicine
  • KANAMORI Heiwa
    First Department of Internal Medicine, Yokohama City University of Medicine
  • TANAKA Masatsugu
    First Department of Internal Medicine, Yokohama City University of Medicine
  • MISHIMA Aki
    First Department of Internal Medicine, Yokohama City University of Medicine
  • KOHARAZAWA Hideyuki
    Division of Blood Transfusion, Yokohama City University Hospital
  • FUJITA Hiroyuki
    First Department of Internal Medicine, Yokohama City University of Medicine
  • FUJISAWA Shin
    First Department of Internal Medicine, Yokohama City University of Medicine
  • MURATA Takashi
    First Department of Internal Medicine, Yokohama City University of Medicine
  • MATSUZAKI Michio
    Division of Blood Transfusion, Yokohama City University Hospital
  • MOHRI Hiroshi
    First Department of Internal Medicine, Yokohama City University of Medicine
  • ISHIGATSUBO Yoshiaki
    First Department of Internal Medicine, Yokohama City University of Medicine

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Other Title
  • 硬膜下血腫，急性硬膜外血腫から救命し得た急性前骨髄球性白血病の１例

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Description

A 22-year-old woman was admitted with purpura. Acute promyelocytic leukemia (APL) with disseminated intravascular coagulation (DIC) was diagnosed. On the 17th day after treatment with all-trans retinoic acid (ATRA), left subdural hematoma developed. Although coagulation abnormalities were still observed, emergency surgery was perfomed. Acute epidural hematoma was confirmed by computed tomographic scan after the operation. A second operation for drainage was successful. Post-operative intracranial hematoma may be caused by rapid decompression induced by surgery, but DIC could also be involved. This case underscored the need for careful consideration of the indications for surgical treatment of such DIC patients, with close follow-up monitoring for the postoperative development of neurological symptoms.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 40 (7), 606-609, 1999

    The Japanese Society of Hematology

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