Positive Seroconversion Syphilis in a Patient with Acute Lymphocytic Leukemia after Allogeneic Bone Marrow Transplantation

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  • NAOHARA Tohru
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • SUZUKI Gaku
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • MASAUZI Nobuo
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • OHIZUMI Hiroko
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • KOBAYASHI Naoki
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • OGASAWARA Masahiro
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • KIYAMA Yoshio
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • SAITOH Masao
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • HIGA Yoshio
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital
  • KASAI Masaharu
    Department of Internal Medecine, Sapporo Hokuyu Hospital, Artificial Organs & Transplantation Hospital

Bibliographic Information

Other Title
  • 同種骨髄移植により血清梅毒反応が陽性化し，治療により陰性化した急性白血病症例
  • ドウシュ コツズイ イショク ニ ヨリ ケッセイ バイドク ハンノウ ガ ヨウ

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Description

An acute lymphocytic leukemia patient underwent allogeneic bone marrow transplantation (BMT) from a sibling who was serologically positive for syphilis. After the donor was administered antibiotic therapy, the titration of treponema pallidum hemagglutination (TPHA) decreased from ×1260 to ×320. Thereafter, the graft consisting of mononuclear cells was transplanted. TPHA of the recipient turned positive on day +63, but became negative 1.5 years after BMT. Although the cause of the seroconversion of TPHA seemed to be the contamination of treponema to the graft, the adoptive transfer could not be ruled out as an another possible cause.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 38 (3), 228-230, 1997

    The Japanese Society of Hematology

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