Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient

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  • OBARA Yoko
    Division of Hematology, Department of Medicine, Jichi Medical School
  • NAGAI Tadashi
    Division of Hematology, Department of Medicine, Jichi Medical School
  • MORI Masaki
    Division of Hematology, Department of Medicine, Jichi Medical School
  • OHMINE Ken
    Division of Hematology, Department of Medicine, Jichi Medical School
  • TOSHIMA Masaki
    Division of Hematology, Department of Medicine, Jichi Medical School
  • KOMATSU Norio
    Division of Hematology, Department of Medicine, Jichi Medical School
  • OZAWA Keiya
    Division of Hematology, Department of Medicine, Jichi Medical School

Bibliographic Information

Other Title
  • 壊そ性膿そうを伴う緑膿菌敗血症を合併した急性骨髄性白血病
  • 壊疽性膿瘡を伴う緑膿菌敗血症を合併した急性骨髄性白血病
  • エソセイ ノウソウ オ トモナウ リョクノウキン ハイケツショウ オ ガッペイ シタ キュウセイ コツズイセイ ハッケツビョウ

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Description

A 56-year-old woman with acute myeloid leukemia had two rapidly growing necrotizing nodules with ulcer formation on her head after the first course of consolidation therapy. Clinical features corresponding to sepsis (e.g., fever) appeared following the development of the skin lesion. Pseudomonas aeruginosa was isolated from the blood as well as pus of the lesion. Based on these findings, a diagnosis of ecthyma gangrenosum was made. Treatment with ciprofloxacin and γ-globulin dramatically improved the patient's clinical features. Since Pseudomonas sepsis with ecthyma gangrenosum is associated with a high mortality rate, it is important to start immediate treatment with appropriate antibiotics.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 45 (10), 1138-1140, 2004

    The Japanese Society of Hematology

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