書誌事項
- タイトル別名
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- Detection of Suppressor Lymphocytes to Hematopoietic Stem Cells in Patients with Aplastic Anemia<br>Pre-treatment of the Bone Marrow Cells with Anti-lymphocyte Globulin
- 再生不良性貧血における造血幹細胞抑制リンパ球の検出--抗リンパ球グロブリンによる骨髄細胞処理法の検討
- サイセイ フリョウセイ ヒンケツ ニ オケル ゾウケツ カンサイボウ ヨクセイ
この論文をさがす
説明
In order to detect suppressor lymphocytes to hematopoietic stem cells, CFU-E colony growth was compared before and after pre-treatment of bone marrow cells with anti-lymphocyte globulin (ALG) and complement in 17 patients with aplastic anemia. Peripheral blood T lymphocytes which suppressed allogeneic CFU-E colony growth were found in 7 cases. In 3 out of these 7 cases, CFU-E colony growth from patients' own marrow cells was enhanced significantly by pre-treatment with ALG and complement, but in the remaining 4 cases no significant enhancement was found. ALG therapy was given 3 cases in whom pre-treatment of bone marrow cells with ALG and complement in vitro enhanced CFU-E colony growth. This therapy was effective in only 2 cases. It is suggested that the results of in vitro tests can not predict the effectiveness of ALG therapy in vivo.
収録刊行物
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- 臨床血液
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臨床血液 26 (3), 357-361, 1985
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390282680009048448
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- NII論文ID
- 130004918289
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:BiqB1MzntFU%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 3024513
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- PubMed
- 3162052
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDLサーチ
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可