書誌事項
- タイトル別名
-
- Deep Vein Thrombosis in Patients with Idiopathic Thrombocytopenic purpura
- ケイカチュウ ニ シンブ ジョウミャク ケッセンショウ オ ヘイハツシタ トク
- —Report of two cases—
この論文をさがす
抄録
The report deals with 2 cases of rare complication of deep vein thrombosis occurred during course of idiopathic thrombocytopenic purpura (ITP). Case 1, a 33-year-old man, entered our hospital because of bleeding tendency and anemia. Laboratory examinations disclosed RBC 2.33×106/cmm, PLT 28×103/cmm, positive direct Coombs'test, positive anti-platelet IgG antibody and both erythroid and megakaryocytic hyperplasia of the bone marrow. Under a diagnosis of Evans'syndrome he was treated with corticosteroid without significant. effect. Yet, a month later he developed a deep vein thrombosis in the left lower extremity, and further 2 months later he had an another episode of thrombosis in the right lower extremity. Case 2, a 63-year old man, has been continuously given corticosteroid since 5 years ago, when a diagnosis of ITP was made with positive anti-platelet antibody. He developed deep vein thrombosis in the left lower extremity following a mild contusion on the left leg when his platelet count was 13,000/cmm.<br>Possible pathogenesis of such deep vein thrombosis is discussed as follows:<br>1) preparatory aggregation of platelet due to presence of large amount of immunocomplexes in the circulation and on the platelet surface<br>2) hypercoagulability due to steroid therapy<br>3) an increase in the vascular platelet reserved pool<br>4) traumatic or other pathogenetic micro-hemorrhage in the vascular wall of large vein with subsequent thrombosis.
収録刊行物
-
- 臨床血液
-
臨床血液 23 (3), 365-370, 1982
一般社団法人 日本血液学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282680009473920
-
- NII論文ID
- 130004498428
-
- NII書誌ID
- AN00252940
-
- COI
- 1:STN:280:Bi2B28blsFw%3D
-
- ISSN
- 18820824
- 04851439
-
- NDL書誌ID
- 2486754
-
- PubMed
- 7202065
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可