鉄芽球性貧血に血小板血症を併発した1例

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タイトル別名
  • A Case of Sideroblastic Anemia Associated with Primary Thrombocythemia
  • テツガキュウセイ ヒンケツ ニ ケッショウバン ケッショウ オ ヘイハツシタ

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A 67-year-old male was admitted to our hospital because of marked thrombocytosis and leukocytosis. Peripheral blood examination revealed RBC 355×104/cmm, Hb 10.7 g/dl, leukocyte count 15,400/cmm with 62% neutrophils, 9% eosinophils and 5% basophils, and platelet count 139.8×104/cmm. Bone marrow aspirate showed hypercellularity of three myeloid elements with 22% erythroblasts and megakaryocyte count 465/cmm. Ringed sideroblasts were seen in 58% of erythroblasts. Chromosome analysis of the bone marrow cells showed no abnormality. Both the activities of ALA synthetase and neutral protease in erythroblasts were reduced.<br>This patient was thought to have two diseases, acquired sideroblastic anemia and thrombocythemia. As both are supposed to be a myeloid stem cell disorder, it seems to be a matter of choice whether he is diagnosed as primary acquired sideroblastic anemia associated with thrombocytosis or primary thrombocythemia associated with acquired sideroblastic anemia.

収録刊行物

  • 臨床血液

    臨床血液 23 (12), 1889-1894, 1982

    一般社団法人 日本血液学会

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